
Brain & Focus
Valerian Root for Sleep: 60 Studies, and Why They Disagreed
The sleep guideline suggests clinicians not use valerian. A 2024 umbrella review found no efficacy evidence. A 2020 meta-analysis of 60 studies says why.
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Nootropics and brain-health supplements measured against real cognitive research.

Brain & Focus
The sleep guideline suggests clinicians not use valerian. A 2024 umbrella review found no efficacy evidence. A 2020 meta-analysis of 60 studies says why.
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Brain & Focus
The follow-up trial analyzed seven men, all employees of the company that makes glycine. What the sleep evidence really shows, and what it measurably did not.
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Brain & Focus
Three sites call themselves the official NeuroPrime store, on three different servers, all registered in the last ten months. No dose disclosed on any.
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Brain & Focus
Every ingredient is quantified — rare and welcome. The problem is the amount: ginkgo at 80 mg, against the 240 mg a day of the trial that found no benefit.
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Brain & Focus
GEM ran 6.1 years in 3,069 people aged 75 and over. Dementia hazard ratio 1.12, and cognitive decline rates were identical in every domain measured.
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Brain & Focus
The sleep meta-analysis asked for more safety data. It arrived as case reports of jaundice, and the NIH now rates ashwagandha a likely cause of liver injury.
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Brain & Focus
The best-known trial found real gains at 8, 12 and 16 weeks. Four weeks after people stopped taking it, the scores fell back.
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Brain & Focus
A crossover trial gave 15 people one large creatine dose during 21 hours awake and scanned their brains. The result is real; the dose is not what you take.
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Brain & Focus
An honest look at magnesium L-threonate (Magtein): the brain-magnesium claim, the thin human evidence, dosing, cost, and whether it beats cheap glycinate.
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Brain & Focus
Melatonin, magnesium, L-theanine, and more: which sleep supplements actually have evidence, the honest order, and why sleep habits beat any pill.
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Brain & Focus
Ashwagandha has some of the best evidence of any calming herb, but it's not magic. What the trials show for stress, cortisol, and sleep, plus who should avoid it.
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Brain & Focus
L-theanine promises calm focus without jitters. What the research actually shows for stress, attention, the caffeine combo, and sleep, plus sensible doses.
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