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SupplementMagazine

Gut & Digestion

Emma Supplement Review: The Label Has 19 Ingredients, Not 6

By Emrah Sümer, Founder & Managing Editor
October 15, 2026
Illustration of a magnifying glass over a long blank label with nineteen lines, six of them highlighted in green
Illustration of a magnifying glass over a long blank label with nineteen lines, six of them highlighted in green

Key takeaways

  • Emma's ingredients page names six ingredients; the Supplement Facts panel lists 19, adding garlic, larch arabinogalactan and eleven vitamins and minerals.
  • Berberine, Emma's largest active at 200 mg, was trialled at 400 mg a day in diarrhea-predominant IBS, where it reduced diarrhea frequency. Emma is sold to relieve constipation.
  • The constipation trials behind two other label ingredients used 12 g of chicory inulin and 1.5 g of magnesium oxide a day. Emma provides 50 mg of inulin and 90 mg of magnesium.
  • Methane on a breath test is linked to constipation in the American College of Gastroenterology's 2020 guideline, which recommends testing for it. We found no trial of Emma for methane or constipation.
  • A single bottle costs $59 one-time ($1.97 a day); the cheapest subscription works out to $1.11 a day. The 90-day guarantee refunds only the first used bottle plus unopened ones.

Search “Emma supplement review” and most of what you find is either the brand’s own testimonials or a video calling it a scam. Neither tells you the thing that matters most: what is in the capsule, how much of it, and whether anyone has tested those amounts. So we read the label.

What Emma is

Emma is a capsule sold by Enclave BioActives, on its own site and in retail stores, for “occasional bloating, gas and constipation”. The dose is two capsules a day, and a bottle holds 30 servings. The pitch rests on one idea: that methane-producing microbes in the gut slow digestion, and that Emma helps rebalance them.

The sales page is built to hurry you. It says “Hurry! Stock is running low due to high demand”, and the checkout page shows a countdown on a “special price”. It also carries an endorsement from a New York gastroenterologist, with the disclosure that she “is a paid member of the Enclave BioActives medical advisory board”. That disclosure is to the brand’s credit; it is still a paid endorsement.

The label has 19 lines, not 6

Emma’s homepage says it “combines six key ingredients”, and its ingredients page describes six: deglycyrrhizinated licorice (DGL), star anise, quercetin, berberine, chicory root inulin and resveratrol. The Supplement Facts panel the brand publishes lists 19.

Ingredient (per 2 capsules)AmountOn the ingredients page?
Berberine hydrochloride200 mgYes
Resveratrol (Japanese knotweed)125 mgYes
Quercetin (dihydrate)125 mgYes
Star anise seed100 mgYes
Garlic bulb100 mgNo
Deglycyrrhizinated licorice root extract50 mgYes
Chicory root inulin50 mgYes
Larch arabinogalactan50 mgNo
Vitamin D20 mcg (100% DV)No
Thiamin20 mg (1,667% DV)No
Riboflavin20 mg (1,538% DV)No
Niacin20 mg (125% DV)No
Vitamin B615 mg (882% DV)No
Folate400 mcg DFE (100% DV)No
Vitamin B12100 mcg (4,167% DV)No
Biotin500 mcg (1,667% DV)No
Pantothenic acid20 mg (400% DV)No
Magnesium (as magnesium oxide)90 mg (21% DV)No
Zinc (as zinc oxide)15 mg (136% DV)No

The NIH Dietary Supplement Label Database has an Emma label entered in July 2024 with the same 19 ingredients and amounts, so the formula does not appear to have changed since then.

One small error worth knowing about: a second panel image on the product page prints thiamin, riboflavin and niacin as “20 mcg”. The brand’s other panel and the NIH record both say 20 mg, and the percentages of the Daily Value printed beside them (1,667% for thiamin, for example) only make sense for milligrams.

None of the extra ingredients is alarming at these amounts. But a shopper comparing “six-ingredient gut formulas” is, in fact, buying a B-complex multivitamin with a gut blend attached.

The three ingredients with real trial data, at a fraction of the trial doses

Three of Emma’s ingredients have published human trials on bowel habits that we could set its amounts against.

IngredientEmma, per dayWhat the trial usedWhat the trial was testing
Berberine hydrochloride200 mg400 mg a day for 8 weeksDiarrhea-predominant IBS
Chicory root inulin50 mg12 g a day (3 x 4 g) for 4 weeksConstipation
Magnesium90 mg, as magnesium oxide1.5 g of magnesium oxide a day for 28 daysChronic constipation

Berberine was tested for the opposite problem

Berberine is the largest active in Emma. A randomized trial of berberine in the gut gave 132 people with diarrhea-predominant irritable bowel syndrome “daily 400 mg of berberine hydrochloride, delivered twice daily”, or a placebo, for eight weeks. Berberine reduced diarrhea frequency (P = 0.032), abdominal pain and urgency.

That is a useful result, but Emma’s own product page headline is “Get Out Damn Poop!”, and its label claims “Promotes regularity”. An ingredient whose best trial shows it reducing diarrhea is an odd centrepiece for a constipation product, and Emma gives half that trial’s daily amount. Our berberine supplement page covers how far berberine products themselves stray from their labels.

Inulin: a trial dose 240 times larger

The chicory inulin trial gave 44 people with constipation 4 g of inulin three times a day, 12 g in total, for four weeks. Stool frequency rose from a median of 3.0 to 4.0 a week compared with placebo (p = 0.038). Two of the authors worked for the company that makes that inulin. Emma’s 50 mg is one 240th of 12 g, by our arithmetic.

Magnesium: more than the whole capsule

A placebo-controlled trial of 34 women with chronic constipation gave 0.5 g of magnesium oxide three times a day, 1.5 g in total; 70.6% improved overall against 25.0% on placebo. Emma lists 90 mg of magnesium from magnesium oxide. By our addition, the label amounts of all 19 ingredients in an Emma serving come to about 1,000 mg, less than the magnesium oxide alone in that trial. If magnesium is what you want for constipation, our page on magnesium citrate uses sets out the doses that were tested.

The methane story is real; Emma has not been tested against it

The marketing is not invented from nothing. The American College of Gastroenterology’s 2020 guideline reports that “a positive methane breath test is associated with constipation (odds ratio = 3.51)” and suggests testing for methane with a breath test “in symptomatic patients with constipation”, while calling the evidence “very low”. It describes methane slowing intestinal transit “in a canine model”. It calls an overgrowth of methane producers intestinal methanogen overgrowth, or IMO.

Emma’s homepage goes further: it says methane “damages the sensitive nerve endings of our gut”. We did not find that claim in the guideline, which describes slower transit and altered muscle contraction.

What is missing is any test of Emma against methane. We found no published trial of Emma, and the brand’s pages do not cite one. The closest evidence for herbal products in gut overgrowth is a retrospective comparison from Johns Hopkins, in which 17 of 37 patients (46%) given a herbal regimen had a negative follow-up breath test against 23 of 67 (34%) given the antibiotic rifaximin, a difference that was not statistically significant (P = .24). Those were different herbal products, chosen by clinicians after a breath test, which is the opposite of buying a capsule without one.

Price and refund terms

On 15 October 2026 the product page listed one bottle at $59 bought once, plus $4.95 shipping; $49 a bottle for three; and $39 for six. Subscription prices were $50.15, $41.65 and $33.15 a bottle. At 30 servings a bottle, that is about $1.11 to $1.97 a day.

The headline is a 90-day money-back guarantee. The policy’s detail matters more: “If you have used more than 1 bottle (a 30-day supply): we will only issue a refund for the first bottle and the unused/unopened bottles that you return.” So on a six-pack, if you use three bottles before deciding it is not working, you are refunded for one used bottle and three unopened ones, not the other two you used. Refunds are made “excluding 10% for shipping and handling fees, if applicable”, and a single-bottle refund is allowed once per product per year.

What we checked on regulators

On 15 October 2026 we searched the FDA’s warning letter database for “Enclave”, “Emma Relief” and “Konscious” (a sister brand named in the refund policy) and found no letters; the same search for an unrelated term returned results, so the search was working. A search of ftc.gov for “Enclave BioActives” found no case, and the BBB’s business search returned no profile under that name. That is the extent of what we checked, and it is not proof that no complaint exists.

Who might consider it, and what to do instead

If you have occasional bloating and want to try something with a money-back guarantee, read the refund rules above first, and know that you are paying mainly for a B-vitamin multivitamin and small amounts of several botanicals, none tested in this combination. If you take prescription medicines, ask a pharmacist before adding berberine.

If constipation is the problem, the ingredients that have been tested for it work at doses Emma does not contain: soluble fiber such as inulin in grams, not milligrams, or magnesium at laxative doses with a doctor’s advice. If you suspect methane or overgrowth, the guideline route is a breath test ordered by a clinician, because the treatment depends on the result. And constipation that is new, persistent, painful or accompanied by blood or weight loss needs a doctor, not a supplement.

The bottom line

Emma’s label tells a different story from its marketing. It is sold as six gut ingredients and contains 19; its biggest active was trialled for diarrhea, at twice the dose; and its fiber and magnesium are present at a small fraction of the amounts that improved constipation in trials. The methane-constipation link is real, but nobody has published a test of Emma against it. We do not link to Emma, and nothing in its label or the trials makes a case for paying $1 to $2 a day for it.

Frequently asked questions

What is in Emma?

Per two-capsule serving, the Supplement Facts panel on the brand's site lists berberine hydrochloride 200 mg, resveratrol 125 mg, quercetin 125 mg, star anise seed 100 mg, garlic bulb 100 mg, deglycyrrhizinated licorice 50 mg, chicory root inulin 50 mg and larch arabinogalactan 50 mg, plus vitamin D, six B vitamins, magnesium 90 mg and zinc 15 mg. The NIH Dietary Supplement Label Database record from July 2024 lists the same 19 ingredients.

Does Emma work for constipation?

We found no published trial of Emma itself. Its ingredients with the clearest human data for bowel habits were tested at much higher amounts: chicory inulin at 12 g a day and magnesium oxide at 1.5 g a day in constipation trials, against 50 mg of inulin and 90 mg of magnesium in Emma. Its largest active, berberine, was trialled in diarrhea-predominant IBS, where it reduced diarrhea.

Is the methane claim real?

Partly. The American College of Gastroenterology's 2020 guideline reports that a positive methane breath test is associated with constipation (odds ratio 3.51) and suggests breath testing for methane in people with constipation. It describes methane slowing transit in an animal model. The brand's homepage goes further, saying methane damages gut nerve endings; we did not find that in the guideline.

How much does Emma cost?

On 15 October 2026 the product page listed $59 for one bottle bought once plus $4.95 shipping, $49 a bottle for three and $39 for six, with subscription prices of $50.15, $41.65 and $33.15 a bottle. One bottle is 30 servings, so that is about $1.11 to $1.97 a day.

What is Emma's refund policy?

The policy offers a 90-day money-back guarantee, but if you used more than one bottle it refunds only the first bottle and the unopened bottles you return, not the second or later bottles you used. Refunds exclude shipping and handling, a single-bottle refund is limited to one per product per year, and after 90 days no refund is given.

Are there regulatory actions against Emma or Enclave BioActives?

On 15 October 2026 we searched the FDA warning letter database for Enclave, Emma Relief and Konscious and found no letters; a search of ftc.gov for Enclave BioActives returned no case; and the BBB business search returned no profile for Enclave BioActives. That is what we checked, not a guarantee that no complaint exists.

Sources

Every claim above is drawn from these primary sources. Last checked July 2026.

  1. 1.Emma by Enclave BioActives, Supplement Facts panel images published on emmarelief.com (ingredients page and product page), read 15 October 2026. Serving size 2 capsules, 30 servings: berberine hydrochloride 200 mg, resveratrol (from Japanese knotweed root extract) 125 mg, quercetin (as quercetin dihydrate) 125 mg, star anise seed 100 mg, garlic bulb 100 mg, deglycyrrhizinated licorice root extract 50 mg, chicory root inulin 50 mg, larch arabinogalactan 50 mg, vitamin D 20 mcg, thiamin 20 mg, riboflavin 20 mg, niacin 20 mg, vitamin B6 15 mg, folate 400 mcg DFE (240 mcg folic acid), vitamin B12 100 mcg, biotin 500 mcg, pantothenic acid 20 mg, magnesium (as magnesium oxide) 90 mg, zinc (as zinc oxide) 15 mg. Checked 15 October 2026
  2. 2.NIH Office of Dietary Supplements, Dietary Supplement Label Database, label 312631 'Emma', entry date 25 July 2024: the same 19 ingredients and amounts, serving 2 capsules, 60 capsules. Checked 15 October 2026
  3. 3.emmarelief.com product page: prices ($59, $49, $39 a bottle one-time; $50.15, $41.65, $33.15 subscription; $4.95 shipping on one bottle), 'Simply take 2 capsules per day', 90-Day Guarantee, 'Hurry! Stock is running low due to high demand', and the disclosure that Dr. Gina Sam 'is a paid member of the Enclave BioActives medical advisory board'. Checked 15 October 2026
  4. 4.emmarelief.com homepage: 'Emma combines six key ingredients' and 'Methane hinders two essential processes responsible for gut motility (digestive speed). It damages the sensitive nerve endings of our gut'. Checked 15 October 2026
  5. 5.emmarelief.com Shipping & Refund Policy: 90-day money back guarantee; 'If you have used more than 1 bottle (a 30-day supply): we will only issue a refund for the first bottle and the unused/unopened bottles that you return'; refunds 'excluding 10% for shipping and handling fees, if applicable'; one single-bottle refund 'per product per year'. Checked 15 October 2026
  6. 6.Chen C, Tao C, Liu Z, et al. A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome. Phytother Res 2015;29:1822-7. PMID 26400188. 132 patients randomized to 'daily 400 mg of berberine hydrochloride, delivered twice daily' or placebo for 8 weeks; reduced diarrhea frequency (P = 0.032), abdominal pain frequency and urgency. Checked 15 October 2026
  7. 7.Micka A, Siepelmeyer A, Holz A, et al. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr 2017;68:82-89. PMID 27492975. 44 volunteers, 3 x 4 g inulin daily (12 g a day) for 4 weeks; stool frequency median 4.0 vs 3.0 per week (p = 0.038). Two authors are from BENEO, the inulin's manufacturer. Checked 15 October 2026
  8. 8.Mori S, Tomita T, Fujimura K, et al. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation. J Neurogastroenterol Motil 2019;25:563-575. PMID 31587548. 34 women, magnesium oxide 0.5 g three times a day (1.5 g a day) for 28 days; overall improvement 70.6% vs 25.0% (P = 0.015). Checked 15 October 2026
  9. 9.Pimentel M, Saad RJ, Long MD, Rao SSC. ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth. Am J Gastroenterol 2020;115:165-178. PMID 32023228. 'a positive methane breath test is associated with constipation (odds ratio = 3.51)'; 'We suggest testing for methane using glucose or lactulose breath tests to diagnose the overgrowth of methane-producing organisms (IMO) in symptomatic patients with constipation (conditional recommendation, very low level of evidence)'; methane infusion slowed transit 'in a canine model'. Checked 15 October 2026
  10. 10.Chedid V, Dhalla S, Clarke JO, et al. Herbal therapy is equivalent to rifaximin for the treatment of small intestinal bacterial overgrowth. Glob Adv Health Med 2014;3:16-24. PMID 24891990. Retrospective comparison; 17 of 37 (46%) herbal-therapy patients vs 23 of 67 (34%) rifaximin patients had a negative follow-up breath test (P = .24). Checked 15 October 2026
  11. 11.Regulatory checks, 15 October 2026: FDA warning letter database searched for 'Enclave', 'Emma Relief' and 'Konscious' (0 results each; the same search for 'kratom' returned 13, confirming the search worked); ftc.gov searched for 'Enclave BioActives' (no case found); BBB business search for 'Enclave BioActives' ('No results'). Checked 15 October 2026